中国药房2016，Vol.27Issue(17)：2431-2432,2433,3.DOI:10.6039/j.issn.1001-0408.2016.17.44
临床药师在厄罗替尼致间质性肺炎患者药物治疗中的作用
Role of Clinical Pharmacists in Therapy for Patient with Interstitial Lung Disease Induced by Erlotinib
李义秀 1娄艳 2章新晶 1熊爱珍1
作者信息
- 1. 南昌大学第二附属医院药剂科，南昌 330006
- 2. 南方医科大学南方医院药剂科，广州 510515
- 折叠
摘要
Abstract
OBJECTIVE:To explore the role of clinical pharmacists in therapy for patient with interstitial lung disease (ILD) induced by erlotinib. METHODS:Clinical pharmacists participated in the therapy for ILD in a patient receiving erlotinib target treat-ment after thoracic vertebra and lumbar radiation,analyzed the cause of ILD and suggested to stop taking imipenem and cilastatin sodium,fluconazol and erlotinib according to lab indexes and patient’s symptom;took prednisone 30 mg,po,qd,for anti-inflam-mation instead of methylprednisolone;adjusted the dose of prednisone to 40 mg/d,and additionally took Carbocisteine oral solution 10 ml,tid,for improving respiratory symptom;panipenem betamipron 1 g,ivgtt,bid,instead of piperacillin sodium and sulbactam sodium. RESULTS:Physicians adopted the suggestions of clinical pharmacists,and the symptom of anhelation and double pneumo-nia recovered;discharged medication plan was erlotinib 150 mg,po,qd. CONCLUSIONS:The patient with radiation history easily suffers from ILD when using erlotinib,and should use erlotinib carefully in the clinic. Clinical pharmacists participated in drug ther-apy and promote safe and rational use of drugs in the clinic.关键词
厄罗替尼/间质性肺炎/放疗/临床药师Key words
Erlotinib/Interstitial lung disease/Radiation therapy/Clinical pharmacist分类
医药卫生引用本文复制引用
李义秀,娄艳,章新晶,熊爱珍..临床药师在厄罗替尼致间质性肺炎患者药物治疗中的作用[J].中国药房,2016,27(17):2431-2432,2433,3.
