中国药理学通报2016，Vol.32Issue(6)：756-759,760,5.DOI:10.3969/j.issn.1001-1978.2016.06.004
微小RNA与胃癌关系的研究进展
Research progress on relationship between microRNA and gastric cancer
摘要
Abstract
Gastric cancer has a high incidence and accounts for a notable proportion of global cancer mortality.The pathogenesis of gastric cancer is complex involving multiple genetic and epige-netic alterations factors.In recent years,studies have also dem-onstrated the aberrant regulation of miRNAs in a variety of tumor pathological processes including the gastric cancer through af-fecting cell proliferation,differentiation and apoptosis.miRNA also plays important roles in gastric cancer growing,invasion, metastasis,and drug resistance of gastric cancers,which might become new biomarkers and potential therapeutic targets in the future.This paper summarizes several important miRNAs in-volved in gastric cancer and also discusses their function.关键词
微小RN A/非编码RN A/胃癌/抗肿瘤/肿瘤标志物/胃癌治疗靶点/基因调控Key words
microRNA/non-coding RNA/gastric cancer/anti-tumor/tumor marker/therapeutic target of gastric cancer/gene regulation分类
医药卫生引用本文复制引用
毛玉娣,丁西平,王华..微小RNA与胃癌关系的研究进展[J].中国药理学通报,2016,32(6):756-759,760,5.基金项目
国家自然科学基金资助项目（No 81372577）；新世纪优秀人才支持计划（NCET-13-0644）；安徽省皖江学者计划资助 （）
