摘要
Abstract
Objective To inuestigate the influence of azithromycin on myocardial injury in children with mycoplasma pneumonia. Methods 80 cases of mycoplasma pneumonia children from February 2010 to February 2015 were randomly selected and divided into the treat-ment group and the control group according to the random number table method,40 cases in each group. The control group was given usual antipyretics and cough medicines and other conventional symptomatic treatment,and on this basis,the treatment group was treated with azithromycin therapy. The changes in the myocardial enzymes,cardiac troponin I(cTnI),myoglobin(MB),different glycogen phospho-rylase isoenzyme(GPBB) of the two groups were observed. Results After treatment,the AST,LDH,CK,a-HBDH and CK-MB of the treatment group were(20. 42 ± 11. 45)U/L,(123. 35 ± 83. 71)U/L,(120. 42 ± 53. 45)U/L,(90. 49 ± 48. 32)U/L and(10. 29 ± 4. 92)U/L, which were significantly lower than(58. 52 ± 21. 19)U/L,(493. 45 ± 93. 82)U/L,(500. 12 ± 143. 45)U/L,(319. 49 ± 118. 42)U/L and (27. 16 ± 11. 92)U/L in the control group( P < 0. 05);the level of cTnI in the treatment group was (0. 12 ± 0. 06)μg/L,which was obviously lower than (0. 29 ± 0. 10)μg/L in the control group( P < 0. 05);the level of MB in the treatment group was (40. 10 ± 19. 24)μg/L,which was obviously lower than(156. 91 ± 71. 23)μg/L in the control group( P < 0. 05);the level of GPBB in the treatment group was(3. 75 ± 1. 02)μg/L,which was obviously lower than(6. 75 ± 2. 13)μg/L in the control group( P < 0. 05). Conclusion Mycoplasma pneumonia children usually have complications of myocardial damage ,azithromycin can effectively reduce or even cure concurrent myocardial injury in the treatment of mycoplasma pneumonia.关键词
支原体肺炎/儿童/阿奇霉素/心肌损伤Key words
mycoplasma pneumonia/children/azithromycin/myocardial injury分类
医药卫生
