中国中西医结合外科杂志2016，Vol.22Issue(3)：219-223,5.DOI:10.3969/j.issn.1007-6948.2016.03.003
急性肠系膜血管缺血性疾病诊断的Meta分析
Diagnosis of Acute Mesenteric Ischemia：A Meta-analysis
宋弢 1沈平 2王西墨2
作者信息
- 1. 天津医科大学研究生院 天津 300070
- 2. 天津市南开医院 天津 300100
- 折叠
摘要
Abstract
Objective To evaluate the value of plasma biomarkers and computed tomography angiography (CTA) in the diagnosis of acute mesenteric ischemia(AMI). Methods The design of this meta-analysis fol⁃lowed the recommendations from the Meta-analysis of Observational Studies in Epidemiology. Summary esti⁃mates of diagnostic accuracy were computed by using a random-effect model. The studies without enough data to reconstruct cross-table were excluded. Results Twenty-four studies were included in the meta-analysis. The pooled sensitivity and specificity for D-lactate was 74%(95% confidence interval [CI] = 61%~84%) and 74%(95%CI = 69%~79%)respectively. The pooled sensitivity and specificity for D-dimer was 96%(95%CI=89%~99%)and 40%(95%CI=33%~47%)respectively. The pooled sensitivity and specificity for intestinal fatty acid binding protein (i-FABP) was 77%(95%CI=66%~86%)and 77%(95%CI=72%~82%)respectively. The pooled sensitivity and specificity for Glutathione S-transferase (GST) was 68%(95%CI=55%~80%)and 85%(95%CI=76%~92%)respectively. The pooled sensitivity and specificity for CTA was 93%(95%CI=90%~96%)and 96%(95%CI=94%~97%)respectively. Conclusion The plasma biomarkers may be helpful for excluding AMI , but their reliability need further confirmation. The CTA had high accuracy in the diagnosis of AMI.关键词
急性肠系膜缺血性疾病/诊断/CT血管造影/血清标志物Key words
Acute mesenteric ischemia/diagnosis/computed tomography angiography/serum biomarkers分类
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宋弢,沈平,王西墨..急性肠系膜血管缺血性疾病诊断的Meta分析[J].中国中西医结合外科杂志,2016,22(3):219-223,5.
