安徽农业科学2016，Vol.44Issue(13)：153-156,4.
基于c-Met激酶的小分子抑制剂研究进展
Research Progress of Small Molecule Inhibitor Based on c-Met Kinase
李丽丽 1艾晓杰2
作者信息
- 1. 上海交通大学农业与生物学院，上海市兽医生物技术重点实验室，上海200240
- 2. 上海美迪西生物医药股份有限公司，上海201299
- 折叠
摘要
Abstract
The HGF/c-Met signaling pathway plays important regulating roles in tumorigenesis, tumor development and transfer, which has be-come the popular target for the research on antitumor drug. We reviewed the research progress of the action mechanism of c-Met signaling pathway and the c-Met inhibitor, aiming at finding an inhibitor with high activity, good selectivity and small side effect, and offering new approach for cancer therapy.关键词
受体酪氨酸激酶/c-Met/小分子抑制剂/抗肿瘤Key words
Receptor tyrosine kinases (RTKs)/c-Met/Small molecule inhibitor/Anti-tumor分类
医药卫生引用本文复制引用
李丽丽,艾晓杰..基于c-Met激酶的小分子抑制剂研究进展[J].安徽农业科学,2016,44(13):153-156,4.
