川北医学院学报2016，Vol.31Issue(3)：288-290,3.DOI:10.3969/j.issn.1005-3697.2016.03.01
前列腺切除术后创面修复细胞来源的初步探讨
The research on the cell source involving in re-epithelialization of prostatic urethra after prostatectomy
摘要
Abstract
Objective:To explore the cells involving in re-epithelialization of prostatic urethra after prostatectomy.Methods:Twelve male canines were randomly divided into two groups and underwent transvesical prostatectomy or sham operation respectively. Wounds were observed with HE and immunohistochemical staining at day 3,week 1 and 2.Results:At day 3,CK34 and PSA expres-sion were negative.CK34 was detected in newly generated epithelium at week 1 ,but PSA was not.At week 2,germinated epithelium formed by CK34 positive cells covered the wound,extending to urothelium.However,there was no PSA positive cell in newly genera-ted epithelium.Conclusion:CK34 positive cells involved in re-epithelialization of prostatic urethra after prostatectomy.PSA positive cells may not play a direct role in that process.关键词
良性前列腺增生/再上皮化/基底细胞Key words
Benign prostate hyperplasia/Re-epithelialization/Basal cells分类
医药卫生引用本文复制引用
丁华,罗光恒,孙兆林..前列腺切除术后创面修复细胞来源的初步探讨[J].川北医学院学报,2016,31(3):288-290,3.基金项目
国家自然科学基金（81260119）；贵州省优秀青年科技基金［黔科合人才团队（2015）20号］ （）
