NGAL 及 MMP9在原发性肝癌患者血清中表达及意义OA北大核心
Detection of peripheral NGAL and MMP9 levels and its clinical significance in primary hepatic carcinoma
目的：探讨原发性肝癌（PHC）患者血清中性粒细胞明胶酶相关脂质运载蛋白（NGAL ）及基质金属蛋白酶9（MMP9）的变化及临床意义。方法采用酶联免疫吸附测定（ELISA）检测47例 PHC 患者（PHC 组）及19例健康体检者健康血清中 NGAL 及 MMP9水平，并分析二者与临床病理的联系，同时使用 ROC 曲线分析二者对 PHC 的诊断价值，Kaplan-Meier 生存曲线分析不同 NGAL 、MMP9水平的生存差异。结果 PHC 组 NG…查看全部>>
Objective To explore the changes of matrix metalloproteinase 9(MMP9) and neutrophil gelatinase associated li-pocalin(NGAL) in primary hepatic carcinoma and its clinical significance .Methods Enzyme-linked immunosorbent assay (ELISA) was used to detect the serum level of MMP9 and NGAL in 47 patients with primary hepatic carcinoma and 19 healthy controls .The association between serum MMP9 and NGAL levels with the clinicopathological features of hepatic carcin…查看全部>>
唐成佳;余天雾
重庆医科大学附属永川医院肝胆外科，重庆永川 404000重庆医科大学附属永川医院肝胆外科，重庆永川 404000
医药卫生
原发性肝癌中性粒细胞明胶酶相关脂质运载蛋白基质金属蛋白酶 9
primary hepatic carcinomaNGALmatrix metalloproteinase 9
《重庆医学》 2016 (17)
2357-2359,3
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