重庆医学2016，Vol.45Issue(17)：2362-2364,3.DOI:10.3969/j.issn.1671-8348.2016.17.019
HGF 蛋白与 C-M et 蛋白在胆管癌中的表达及临床意义
Expression and clinical significance of HGF and C-Met in cholangiocarcinoma
王金 1赵一洁 2崔广宾 2尚培中1
作者信息
- 1. 中国人民解放军第二五一医院普通外科，河北张家口 075000
- 2. 河北北方学院，石家庄 075061
- 折叠
摘要
Abstract
Objective To investigate the expression and clinical significance of HGF and C-Met in cholangiocarcinoma .Meth-ods The levels of HGF and C-Met were measured by ELISA ,the expression of HGF and C-Met in cholangiocarcinoma and health control was detected by immunohistochemistry .Results The preoperative levels of HGF and C-Met in cholangiocarcinoma were higher than the health control(P< 0 .05) .Compared with the preoperative state ,the levels of HGF and C-Met in cholangiocarcino-ma on the 3rd day after operation did not change significantly .However ,the levels of HGF and C-Met on the postoperative 7th and 10th day decreased obviously .In addition ,the expression of HGF and C-Met in cholangiocarcinoma was 76 .2% ,81 .0% ,respective-ly ,which is higher than that in normal tissue ( P < 0 .01) .Conclusion There is an abnormal expression of HGF and C-Met in cholangiocarcinoma ,which may be related to the incidence and development of cholangiocarcinoma .关键词
胆管肿瘤/肝细胞生长因子/C-Met 蛋白/临床病理特征Key words
cholangiocarcinoma/hepatocyte growth factor/C-Met/clinical and pathological features分类
医药卫生引用本文复制引用
王金,赵一洁,崔广宾,尚培中..HGF 蛋白与 C-M et 蛋白在胆管癌中的表达及临床意义[J].重庆医学,2016,45(17):2362-2364,3.
