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白藜芦醇对动物表观遗传学调控的作用机制

张卫兵 张蓉 屠焰 刁其玉

动物营养学报2016,Vol.28Issue(5):1302-1308,7.
动物营养学报2016,Vol.28Issue(5):1302-1308,7.DOI:10.3969/j.issn.1006-267x.2016.05.003

白藜芦醇对动物表观遗传学调控的作用机制

The Mechanism of Resveratrol in Epigenetics Regulation in Animals

张卫兵 1张蓉 1屠焰 1刁其玉1

作者信息

  • 1. 中国农业科学院饲料研究所,农业部饲料生物技术重点实验室,奶牛营养学北京市重点实验室,北京 100081
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摘要

Abstract

Resveratrol is a kind of non⁃flavonoid phenolic compounds, and is a kind of natural plant anti⁃toxin, which widely exists in many plants. Resveratrol has various bioactivities and pharmacological effects, such as antioxidant activity, anticancer activity, neuroprotective activity, cardioprotective capacity and anti⁃aging activ⁃ity. Recent studies indicated that these activities were largely accomplished by epigenetic modifications in the regulation of gene expression. In this paper, we summarized the main mechanism of epigenetic modification and the research progress of resveratrol in animals and humans gene DNA methylation, histone acetylation and miRNA. From the aspects of epigenetic modification, we reviewed the pathway of resveratrol in animals and humans.

关键词

白藜芦醇/表观遗传学/调控/DNA甲基化/组蛋白乙酰化/微小RNA

Key words

resveratrol/epigenetics/regulation/DNA methylation/histone acetylation/miRNA

分类

农业科技

引用本文复制引用

张卫兵,张蓉,屠焰,刁其玉..白藜芦醇对动物表观遗传学调控的作用机制[J].动物营养学报,2016,28(5):1302-1308,7.

基金项目

公益性行业(农业)科研专项“南方地区幼龄草食畜禽饲养技术研究(201303143)”;奶牛产业技术体系北京市创新团队营养岗位 ()

动物营养学报

OA北大核心CSCDCSTPCD

1006-267X

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