中国妇幼健康研究2016，Vol.27Issue(6)：723-725,3.DOI:10.3969/j.issn.1673-5293.2016.06.017
西安市儿童医院92例难治性肺炎支原体肺炎临床特点分析
Clinical features of 92 cases of refractory mycoplasma pneumoniae pneumonia in Xi’ an Children’ s Hospital
孙欣荣 1孙芳 1王立军 1余宏川1
作者信息
- 1. 西安市儿童医院呼吸一科陕西西安710003
- 折叠
摘要
Abstract
Objective To analyze the clinical features of refractory mycoplasma pneumoniae pneumonia (RMPP) and look for indictors revealing poor efficacy of conventional glucocorticoid therapy .Methods Retrospective analysis was conducted on the clinical features of 92 cases of RMPP .Comparison was made on the clinical data of cases requiring combination treatment with intravenous gamma globulin or not.Results RMPP was common in preschool and school-age children, and children aged 3-9 years occupied 78.26%(72/92) with main symptoms of recurrent fever and cough .Cases with blood leukocyte count in normal range occupied 73.91%(68/92), and high-sensitivity C-reactive protein increased significantly .The most common extrapulmonary manifestation was pleural effusion .After confirmed diagnosis methylprednisolone (2mg/kg per day) was given.There were 75 cases (84.78%) declining to normal body temperature next day after medication.Twenty-two cases still had fever 3 days after use of methylprednisolone (2mg/kg per day) (fever again after drug stop), and combination with intravenous gamma globulin was needed .Clinical and experimental results of cases only accepting methylprednisolone and those accepting methylprednisolone combined with gamma globulin were compared , and the difference in primary value of calcitionin was significant (t=-3.24,P<0.05).Conclusion Conventional doses of methylprednisolone can achieve better clinical results in treatment of RMPP patients.Procalcitonin increasing may require joint therapy with intravenous gamma globulin .关键词
难治性/肺炎支原体肺炎/临床特点/降钙素原Key words
refractory/mycoplasma pneumoniae pneumonia/clinical features/procalcitonin分类
医药卫生引用本文复制引用
孙欣荣,孙芳,王立军,余宏川..西安市儿童医院92例难治性肺炎支原体肺炎临床特点分析[J].中国妇幼健康研究,2016,27(6):723-725,3.
