摘要
Abstract
Objective To analyze the induced factors, clinical diagnosis and treatment of 10 cases of amniotic fluid embolism (AFE). Methods Retrospective study was carried out among 10 cases of AFE occurred in Beijing Gynecology and Obstetrics Hospital Affiliated to Capital Medical University between January 2003 and December 2013.Results The incidence of AFE was 0.79/10 000, and the case fatality rate was 20%.All of the patients had ruptured membranes before attack .Five patients had severe preeclampsia , and 8 had pregnancy history .Maternal herald signs included respiratory system ( short of breath , bucking , dyspnea , descending of saturation of blood oxygen), cardiovascular system (syncope, malaise, cardiorespiratory arrest) and/or hemorrhage.Every case suffered continuous bleeding . Surgical intervention to achieve hemostasis was necessary in 7 cases, and all of them had hysterectomy ultimately .Conclusion AFE is a rare but extremely serious disease .Risk factors for AFE include male fetus , rupture of membrane , severe preeclampsia , etc.The diagnosis of AFE should be based on clinical manifestations and signs , and the cases should be rescued as soon as they were diagnosed .At the same time, antianaphylaxis treatment , respiratory and circulation support , supplementary of blood volume and correction of coagulation disorders need to be provided .Hysterectomy is performed if necessary .关键词
羊水栓塞/高危因素/诊断/治疗Key words
amniotic fluid embolism ( AFE)/high risk factor/diagnosis/treatment分类
医药卫生
