海南医学院学报2016，Vol.22Issue(15)：1630-1632,1636,4.DOI:10.13210/j.cnki.jhmu.20160422.004
丹参注射液辅助治疗病毒性心肌炎的抗炎及抗氧自由基的效应研究
Anti-inflammation and anti-oxygen free radical effect of adjuvant Danshen injection treatment on viral myocarditis
摘要
Abstract
Objective:To analyze the anti-inflammation and anti-oxygen free radical effect of adjuvant Danshen injection treatment on viral myocarditis.Methods:A total of 90 children with viral myocarditis treated in our hospital from January 2014 to January 201 6 were included in the research and randomly divided into observation group (n =45)and control group (n =45) according to the different treatment.Control group received clinical routine therapy for viral myocarditis,observation group re-ceived adjuvant Danshen injection treatment,and then levels of IL23/IL-1 7 inflammatory axis as well as cytokines,oxidation and anti-oxidation indexes,myocardial enzyme and illness-related proteins were compared between two groups.Results:Serum IL-1 7,IL-23,IL-1β,IL-6 and TNF-αvalues of observation group were lower than those of control group (P <0.05);serum MDA,AOPP and NO values of observation group after treatment were lower than those of control group while SOD and T-AOC values were higher than those of control group (P <0.05);serum cTnT,CK-MB,MCP-1 and H-FABP values of obser-vation group after treatment were lower than those of control group (P <0.05).Conclusions:Adjuvant Danshen injection treat-ment for children with viral myocarditis can exert positive anti-inflammation and anti-oxygen free radical function,and it plays a positive role in myocardial protection.关键词
病毒性心肌炎/丹参注射液/抗炎/抗氧自由基Key words
Viral myocarditis/Danshen injection/Anti-oxygen free radical分类
医药卫生引用本文复制引用
梁文宝,陈简..丹参注射液辅助治疗病毒性心肌炎的抗炎及抗氧自由基的效应研究[J].海南医学院学报,2016,22(15):1630-1632,1636,4.基金项目
2012年广东省建设中医药强省科研课题(20122095) （20122095）
