海南医学院学报2016，Vol.22Issue(15)：1752-1754,1757,4.DOI:10.13210/j.cnki.jhmu.20160517.012
肝炎肝硬化患者术中两种麻醉方式对肝肾功能及免疫指标的影响
Effect of two kinds of anesthesia methods during operation on hepatic and renal function and immune indexes of hepatitis hepatocirrhosis patients
摘要
Abstract
Objective:To discuss the effect of two kinds of anesthesia methods during operation on hepatic and renal function and immune indexes of hepatitis hepatocirrhosis patients and then to provide basis for selection of clinical anesthesia appropriate schemes.Method:A total of 50 cases with hepatitis hepatocirrhosis who underwent splenectomy disconnection op-eration in our hospital were selected and then were divided into study group (25 cases)and control group (25 cases).Patients in study group were given intravenous inhalational anesthesia treatment,while patients in control group were given total intrave-nous anesthesia treatment.Hepatic and renal function and immune function of patients were compared 2 h before anesthesia、in-duction and 1 d after operation.Results:Before anesthesia,hepatic and renal function indexes of patients in both groups showed no statistical significant difference (P >0.05).Two hours after induction and 1 d after operation,albumin levels of patients in study group were significantly higher than that in control group;while 1 d after operation,alanine aminotransferase levels of patients were significantly lower than that in control group(P <0.05).Intra-group hepatic function variation range at different time in study group was significantly less than that in control group (P <0.05).Two hours after induction and 1 d after opera-tion,BUN,Creatinine levels of patients in study group were significantly lower than that in control group (P <0.05).Intra-group renal function variation range at different time in study group was also significantly less than that in control group (P <0.05).Before anesthesia,CD4 + ,CD8 + ,CD4 +/CD8 + levels in both groups showed no statistical significant difference(P >0. 05 ),2 h after induction and 1 d after operation,CD4 + ,CD4 +/CD8 + levels of patients in study group were significantly higher than that in control group (P <0.05).Conclusions:Effect of sevoflurane intravenous inhalational anesthesia treatment on he-patic and renal function and immune function of hepatitis hepatocirrhosis patients are relatively more significant,which is suit-able for hepatitis hepatocirrhosis patients .关键词
肝炎肝硬化/肝肾功能/免疫功能/七氟醚Key words
Hepatitis hepatocirrhosis/Hepatic and renal function/Immune function/Sevoflurane分类
医药卫生引用本文复制引用
周章,宋俊,阮云丹..肝炎肝硬化患者术中两种麻醉方式对肝肾功能及免疫指标的影响[J].海南医学院学报,2016,22(15):1752-1754,1757,4.基金项目
国际自然科学基金(81202128) （81202128）
