实用心电学杂志2016，Vol.25Issue(3)：210-212,3.DOI:10.13308/j.issn.2095-9354.2016.03.013
心房颤动患者抗凝治疗前后微栓子及血浆D-二聚体水平观察
Observation on microembolic signal and D-dimer level of atrial fibrillation patients before and after anticoagulant therapy
徐云 1王兵 1蒋丽娇 1陆小平 1赵晓英 1王芳1
作者信息
- 1. 215128 江苏 苏州，苏州市吴中人民医院心内科
- 折叠
摘要
Abstract
Objective To observe the microembolic signal(MES)and D-dimer level of atrial fi-brillation patients before and after warfarin anticoagulant therapy.Methods A total of 40 persistent atrial fibrillation patients with CHADS2 score≥1 were selected.Each of research object underwent MES monitoring and D-dimer level detection before and after warfarin anticoagulant therapy.We compared the results before and after the treatment.Results Before anticoagulant therapy,there were 1 2 cases with positive MES and 28 with negative MES;after the treatment,5 cases were posi-tive in MES and 35 were negative.The positive rate of MES significantly decreased after anticoagulant therapy(30.0% vs.12.5%,χ2 =3.66,P <0.05).The level of D-dimer was (273 ±81 )μg/L before anticoagulant therapy and (170 ±67)μg/L after the therapy.The level of plasmatic D-dimer significantly reduced after the treatment(t =10.09,P <0.05 ).Conclusion Both of MES and D-dimer level can be regarded as risk evaluation indicators of embolism in atrial fibrillation patients.关键词
心房颤动/华法林/抗凝治疗/微栓子/D-二聚体Key words
atrial fibrillation/warfarin/anticoagulant therapy/mcroembolic signal/D-dimer分类
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徐云,王兵,蒋丽娇,陆小平,赵晓英,王芳..心房颤动患者抗凝治疗前后微栓子及血浆D-二聚体水平观察[J].实用心电学杂志,2016,25(3):210-212,3.
