江苏实用心电学杂志2016，Vol.25Issue(3)：217-221,5.DOI:10.13308/j.issn.2095-9354.2016.03.015
他汀应用于心房颤动防治的研究进展
Advances of research on statin’s application in atrial fibrillation control
汪永生 1张晓红1
作者信息
- 1. 230061 安徽 合肥，合肥市第一人民医院心血管内科
- 折叠
摘要
Abstract
Atrial fibrillation(AF)is the most common public health problem.It has been re-vealed by research that inflammation and oxidative stress of cardiac muscle cell involve in the struc-tural and electrical remodeling of atrium,which becomes the underlying pathogenesis of AF further-ly.Statins is a kind of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor.Besides the effi-cacy of lipid-lowering,statin drugs are also anti-inflammatory and anti-oxidative-stress,which im-proves the remodeling of atrium and thus reduces the incidence of AF.However,the anti-arrhythmic property of statin has not been completely illuminated in clinical practice.Conclusions about its ap-plication in the primary or secondary prevention of AF remain controversial.关键词
心房颤动/他汀/炎症/氧化应激Key words
atrial fibrillation/statin/inflammation/oxidative stress分类
医药卫生引用本文复制引用
汪永生,张晓红..他汀应用于心房颤动防治的研究进展[J].江苏实用心电学杂志,2016,25(3):217-221,5.
