农药学学报2016，Vol.18Issue(3)：291-298,8.DOI:10.16801/j.issn.1008-7303.2016.0040
新型含苯并咪唑的（S，S）-2,8-二氮杂双环[4.3.0]壬烷类衍生物的合成及生物活性
Synthesis and bioactivity of (S, S)-2,8-diazabicyclo [4.3.0] nonane containing benzimidazole moiety
摘要
Abstract
A series of novel (S, S)-2,8- diazabicyclo [4.3.0] nonane containing benzimidazole moiety was synthesized and their structures were determined by 1H NMR and HRMS. The biological activity results showed that these compounds possessed moderate antifungal activity to some plant pathogenous fungi and moderate insecticidal activity against Mythimna separata Walker and Culex pipiens pallens. Compounds 6e and 6f exhibited good antibacterial activity against Sclerotinia sclerotiorum, Phytophthora infestans and Fusarium graminearum. The lethality rates of compounds 6e and 6k against Mythimna separata Walker were 100% at 200 mg/L and the lethality rates of compounds 6h and 6k against C. pippiens pallens were 75% at 2 mg/L.关键词
苯并咪唑/(S,S)-2,8-二氮杂双环4.3.0壬烷/抗真菌活性/杀虫活性Key words
(S, S)-2, 8-diazabicyclo[4.3.0]nonane/benzimidazole/antifungal activity/insecticidal activity分类
化学化工引用本文复制引用
万莹莹,魏巍,陈有为,刘敬波,程丹丹,熊丽霞,于淑晶,李玉新,李正名..新型含苯并咪唑的（S，S）-2,8-二氮杂双环[4.3.0]壬烷类衍生物的合成及生物活性[J].农药学学报,2016,18(3):291-298,8.基金项目
Fond project：Project supported by the National Science Foundation of China (No.31370039) （No.31370039）
