中国医疗设备2016，Vol.31Issue(6)：56-59,4.DOI:10.3969/j.issn.1674-1633.2016.06.012
IMD、脑钠肽的水平在老年慢性心力衰竭中的临床意义
Clinical Signiifcance of Application of Serum NT-proBNP and IMD in Diagnosis of Elderly Patients with Chronic Heart Failure
摘要
Abstract
ObjectiveTo measure the change of Intermedin (IMD) and N-Terminal pro-Brain Natriuretic Peptide (NT-proBNP) so as to explore their clinical significance in diagnosis of the elderly patients with chronic heart failure (CHF).Methods According to the American New York Heart Association (NYHA) standard, the elderly CHF patients were divided into Cardiac Function Grade I Group, Grade II Group, Grade III Group and Grade IV Group for comparative analysis. The level of serum IMD and NT-proBNP in elderly CHF patients and the normal Control Group were measured.Results IMD of Grade IV Group was lower than that of Grade I, II Group and III Group with statistically significant difference (P<0.05). IMD of Grade III Group was lower than that of Grade I and II Group with statistically signiifcant difference (P<0.05). The level of NT-proBNP in CHF patients was signiifcantly higher than the normal Control Group (P<0.01), and was increased following the increase of grade (P<0.05). The plasma levels of IMD and NT-proBNP were negatively correlated (r=-0.573,P<0. 001).Conclusion The changes of IMD and NT-proBNP contribute to the understanding of the severity and prognosis assessment of elderly patients with chronic heart failure. Patients’ lower IMD indicates lower prognosis assessment.关键词
中介素/N末端B型脑钠肽前体/心力衰竭Key words
intermedin/N-terminal pro-brain natriuretic peptide/chronic heart failure分类
医药卫生引用本文复制引用
何凯..IMD、脑钠肽的水平在老年慢性心力衰竭中的临床意义[J].中国医疗设备,2016,31(6):56-59,4.基金项目
重庆市医学科研项目资助（2013－2－118）。 （）
