中国全科医学2016，Vol.19Issue(16)：1907-1910,4.DOI:10.3969/j.issn.1007-9572.2016.16.013
乌鲁木齐地区人群碘营养状态与甲状腺癌的关系研究
Correlation Between Iodine Status and Thyroid Cancer of People in Urumqi
摘要
Abstract
Objective To study the correlation between iodine nutritional status and thyroid cancer of people in Urumqi. Methods We recruited 158 patients who were confirmed with benign thyroid nodules and 156 patients who were confirmed with thyroid cancer after surgery and pathological confirmation in the First Affiliated Hospital of Xinjiang Medical University from March to December 2014 as benign thyroid nodule group and thyroid cancer group respectively. We also enrolled 301 patients who were confirmed with normal thyroid gland form by thyroid ultrasound in the physical examination center in the Second Affiliated Hospital of Xinjiang Medical University in the same period. The general data,urine iodine,thyroid function and thyroid autoantibody expression of the three groups were recorded and compared. Risk factors for thyroid cancer were investigated by multivariate Logistic regression analysis. Results The three groups were significantly different in gender and age(P﹤0. 05), but were not significantly different in ethnic group(P﹥0. 05). The three groups were significantly different in the levels of TT3, TT4,TSH,TgAb and TPOAb(P﹤0. 05). The average urine iodine level of the 615 subjects was 261. 50(221. 50)μg/L, with 257. 60(169. 35)μg/L for normal thyroid gland form group,261. 05(263. 42)μg/L for benign thyroid nodule group and 297. 90(374. 40)μg/L for thyroid cancer group;the differences among the three groups were significant(P ﹤0. 05), with thyroid cancer group significantly different from benign thyroid nodule group and normal thyroid gland form group and benign thyroid nodule group significantly different from normal thyroid gland form group( P ﹤0. 05 ) . Multivariate Logistic regression analysis showed that females,abnormal serum TgAb level and excessive iodine intake were risk factors for thyroid cancer( P﹤ 0. 05). Conclusion The iodine deficiency among the population in Urumqi has been substantially corrected and has surpassed appropriate quantity. Females,abnormal serum TgAb level and excessive iodine intakeare risk factors for thyroid cancer,so we recommend the intake of food containing iodine and iodised salt be controlled in the diet of people in Urumqi.关键词
碘/甲状腺肿瘤/乌鲁木齐Key words
Iodine/Thyroid neoplasms/Urumqi分类
医药卫生引用本文复制引用
张润晓,杨雯雯,张丽..乌鲁木齐地区人群碘营养状态与甲状腺癌的关系研究[J].中国全科医学,2016,19(16):1907-1910,4.基金项目
新疆维吾尔自治区自然科学基金资助项目（2013211A057）---乌鲁木齐地区碘和硒营养状态与甲状腺癌的相关性研究 （）
