中国全科医学2016,Vol.19Issue(17):1998-2001,4.DOI:10.3969/j.issn.1007-9572.2016.17.003
Let-7家族与肺部疾病研究进展
Research Progression of Let-7 and Pulmonary Diseases
摘要
Abstract
MicroRNA( miRNA) is a class of endogenous non coding RNA and is widely distributed. It involves a series of important processes in life activity through the regulation of gene expression patterns,including cell proliferation, apoptosis,differentiation and individual development. Let-7 family is the second member of the miRNA family,discovered after Lin - 4 in 2000,and is thought to be related to the occurrence and development of tumor,cardiovascular diseases,viral infections and pulmonary diseases,especially. In this review,we focused on the recent research progress of miRNA Let-7 family and pulmonary diseases such as pulmonary cancer,bronchopulmonary dysplasia,pulmonary injury,pulmonary fibrosis and pulmonary inflammation.关键词
微 RNAs/基因调控/肺疾病/Let-7Key words
MicroRNAs/Gene regulation/Lung diseases/Let-7分类
医药卫生引用本文复制引用
罗妍妍,吴升华,陈筱青..Let-7家族与肺部疾病研究进展[J].中国全科医学,2016,19(17):1998-2001,4.基金项目
国家自然科学基金资助项目 ()