中国药房2016，Vol.27Issue(18)：2538-2539,2540,3.DOI:10.6039/j.issn.1001-0408.2016.18.30
ICP-OES法快速测定复方氯化钠注射液中氯化钾和氯化钙的含量
Rapid Contents Determination of Potassium Chloride and Calcium Chloride in Compound Sodium Chloride Injection by ICP-OES
摘要
Abstract
OBJECTIVE:To establish a method for the rapid contents determination of potassium chloride and calcium chloride in Compound sodium chloride injection. METHODS:After diluted in appropriate way,Compound sodium chloride injection was sampled directly and contents of potassium chloride and calcium chloride were determined simultaneously by ICP-OES. The powder was 1 300 W,plasma gas flow rate was 15 L/min,auxiliary cooling gas flow was 0.2 L/min,atomizer flow rate was 0.8 L/min, the peristaltic pump rate was 0.8 L/min,atomizer pressure was 315 kPa,and the observation was axial observation,analysis spec-tral lines of potassium and calcium were 766.490 nm and 315.887 nm. RESULTS:The linear ranges of potassium and calcium were 1.0-12.0 mg/L (r=0.999 7 and 0.999 9);RSDs of precision and reproducibility tests were lower than 1%;recoveries were 98.5%-100.5%(RSD=0.59%,n=9)and 99.3%-102.3%(RSD=0.98%,n=9). CONCLUSIONS:The method is simple,rapid and simple,and can be used for the quality control of Compound sodium chloride injection.关键词
电感耦合等离子体发射光谱法/复方氯化钠注射液/氯化钾/氯化钙/含量测定Key words
ICP-OES/Compound sodium chloride injection/Potassium chloride/Calcium chloride/Content determination分类
医药卫生引用本文复制引用
周伟明,李华锦,程国华..ICP-OES法快速测定复方氯化钠注射液中氯化钾和氯化钙的含量[J].中国药房,2016,27(18):2538-2539,2540,3.基金项目
国家自然科学基金资助项目 （）
