中国中医药信息杂志2016，Vol.23Issue(7)：22-25,4.DOI:10.3969/j.issn.1005-5304.2016.07.006
痔瘘洗剂联合加味四黄膏治疗肛窦炎临床研究
Clinical Study onZhilou Lotion Combined with ModifiedSihuang Ointment in Treatment of Anal Cryptitis
摘要
Abstract
Objective To observe the clinical efficacy and safety ofZhilou Lotion combined with modified Sihuang Ointment in treatment of anal cryptitis.MethodsOne hundred patients with anal cryptitis were randomly divided into observation group and control group, with 50 cases in each group. The control group was given propylene dispersible tablets oral and topicalHuazhi embolism. The observation group received steaming and hip bath with Zhilou Lotion combined with modifiedSihuang Ointment topical external application treatment, 7 days as a course of treatment and 2 courses successive. The TCM syndrome scores of two groups were compared before and after treatment to evaluate the clinical efficacy. The remission time of symptoms, hospitalization time, recurrence rate in 6 months and adverse reactions were observed.Results After treatment, the TCM syndrome scores of two groups were improved (P<0.01), and the scores in the observation group was lower than those in the control group (P<0.01). The total effective rate was 96.0% (48/50) in the observation group, and 80.0% (40/50) in the control group, with statistical significance (P<0.01). The remission time of anal edema, anal dampness, anal pain and anal fall-swell in observation group was obviously shorter than that in the control group, with statistical significance (P<0.01). The average hospitalization time was (15.25±2.78) days in the observation group and (18.46±3.41) days in the control group, the difference was significant (P<0.01). In the observation group, the recurrence rate was 0, 0 and 2.0% in 2, 4, 6 months follow-up, while that was 4.0%, 12.0% and 16.0% in the control group, respectively. The recurrence rates of the control group in 4 months and 6 months were higher than those of the observation group (P<0.05). No significant adverse reactions occurred in the two groups.Conclusion Zhilou Lotion combined with modifiedSihuang Ointment has good clinical efficacy in treatment of anal cryptitis, with low recurrence rate and high safety.关键词
痔瘘洗剂/加味四黄膏/肛窦炎/湿热下注Key words
Zhilou Lotion/modifiedSihuang Ointment/anal cryptitis/downward flow of dampness-heat分类
医药卫生引用本文复制引用
胡建文,梁小霞,桂香..痔瘘洗剂联合加味四黄膏治疗肛窦炎临床研究[J].中国中医药信息杂志,2016,23(7):22-25,4.基金项目
深圳市宝安区科技计划社会公益（医疗卫生）项目 （）
