中国中医药信息杂志2016，Vol.23Issue(7)：101-103,3.DOI:10.3969/j.issn.1005-5304.2016.07.026
3种含重金属制剂的微生物限度检查方法的验证
Verification of Microbial Limit Test Methods for Three Kinds of Preparations with Heavy Metals
摘要
Abstract
Objective To establish the methods of microbial limit test for three kinds of preparations with heavy metals, such asDingxian Pills,Pizhi Lotion andJiawei Huangqin Ointment.Methods According to Chinese Pharmacopoeia 2010, the recovery rates of bacteria, fungus and yeast treated by three preparations were detected. And the methods of testing control bacteria were also validated.Results Culture medium dilution method was proved to be applicable forDingxian Pills. Culture medium dilution method combined with pre-filtration method was proper for Pizhi Lotion. And the extraction method was adopted forJiawei Huangqin Ointment. The recovery rates of these five validation strains reached 70% by appropriate methods. And the same methods were used for validation of the control bacteria.Conclusion The methods of microbial limit test for these three different preparations were established through this study.关键词
培养基稀释法/萃取法/重金属/微生物限度Key words
culture medium dilution method/extraction method/heavy metals/microbial limit test分类
医药卫生引用本文复制引用
管敏,周琴妹..3种含重金属制剂的微生物限度检查方法的验证[J].中国中医药信息杂志,2016,23(7):101-103,3.基金项目
江苏省中医院科研项目 （）
