国际口腔医学杂志2016，Vol.43Issue(4)：401-405,5.DOI:10.7518/gjkq.2016.04.008
右美托咪定滴鼻应用于小儿唇腭裂手术的效果研究
Effects of intranasal dexmedetomidine for children undergoing cleft lip and palate repair surgery
刘云 1李贞贞 1杨旭东1
作者信息
- 1. 北京大学口腔医院麻醉科 北京 100081
- 折叠
摘要
Abstract
Objective To observe the preoperative sedation and postoperative agitation effects of intranasal dexmedeto-midine premedication on children undergoing cleft lip or palate repair surgery. Methods One hundred and twenty children aged 6 months to 3 years old undergoing elective cleft lip or palate repair surgery were randomly allocated into two groups. Thirty minutes before operation, patients in group A received intranasal placebo(0.9% saline) 0.02 mL·kg-1. Patients in group B received intranasal dexmedetomidine 2μg·kg-1. The children’s time for falling asleep was observed. The preoperative sedation score, the profile of mood state apart from parents, the receipt score of face mask for anesthesia induction and the postoperative agitation score were evaluated. Results The time for children in group B in falling asleep was (10.52± 5.34) min. The preoperative sedation score, the profile of mood state apart from parents, the receipt score of face mask and the postoperative agitation in group B were better than group A(P<0.05). Conclusion Premedication with intranasal dexmedetomidine 2μg·kg-1 for children undergoing cleft lip or palate repair surgery produces good preoperative sedation and postoperative agitation effects.关键词
右美托咪定/滴鼻/小儿/唇腭裂/术前镇静Key words
dexmedetomidine/intranasal/children/cleft lip and palate/preoperative sedation分类
医药卫生引用本文复制引用
刘云,李贞贞,杨旭东..右美托咪定滴鼻应用于小儿唇腭裂手术的效果研究[J].国际口腔医学杂志,2016,43(4):401-405,5.
