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内科保守治疗与不同手术时机去骨瓣减压治疗大面积脑梗死的对比研究

陆梦如 曾丽 李家鑫 蒋小英

中国实用神经疾病杂志2016,Vol.19Issue(12):4-6,3.
中国实用神经疾病杂志2016,Vol.19Issue(12):4-6,3.

内科保守治疗与不同手术时机去骨瓣减压治疗大面积脑梗死的对比研究

Comparative study of conservative treatment vs decompressive craniectomy in different times of operation for the treatment of massive cerebral infarction

陆梦如 1曾丽 1李家鑫 1蒋小英1

作者信息

  • 1. 广西医科大学第一附属医院神经重症ICU南宁 530021
  • 折叠

摘要

Abstract

Objective To compare the clinical efficacy of conservative treatment and decompressive craniectomy in differ‐ent times of operation for massive cerebral infarction patients .Methods Depending on the variable treatment strategy conditions and different times of surgery ,60 cases with acute massive cerebral infarction in our hospital were selected and divided into three groups ,20 cases in each group .Cases in group A were treated with conservative therapy ,cases in group B received de‐compressive craniectomy surgery before the formation of cerebral hernia and the rest in group C underwent decompressive craniectomy surgery after cerebral hernia occurred .Then the NIHSS ,GCS ,BI ,mRS scores as well as recovery status ,mortality and prognosis of the three groups were comparatively analyzed .Results After one‐month treatment ,the NIHSS scores were ob‐viously decreased in all three groups ,especially in group C compared with that before treatment ;and the differences between three groups were significant (P<0 .05) .Furthermore ,the three groups showed statistical differences in terms of GCS ,BI and mRS scores ,and group C got the highest GCS and BI scores and the lowest mRS scores (P<0 .05) .After six‐month treat‐ment ,significant differences were found between three groups as for mortality ,functional recovery and prognosis (P<0 .05) . Conclusion Referring to clinical efficacy and short‐term prognosis ,decompressive craniectomy may take advantages over conser‐vative treatment for the treatment of large cerebral infarction .And carrying out operation at the early stage of cerebral hernia should be beneficial for improving survival rate ,functional recovery and prognosis .

关键词

大面积脑梗死/保守治疗/去骨瓣减压手术/手术时机

Key words

Massive cerebral infarction/Conservative treatment/Decompressive craniectomy/Operation time

分类

医药卫生

引用本文复制引用

陆梦如,曾丽,李家鑫,蒋小英..内科保守治疗与不同手术时机去骨瓣减压治疗大面积脑梗死的对比研究[J].中国实用神经疾病杂志,2016,19(12):4-6,3.

中国实用神经疾病杂志

1673-5110

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