中国实用神经疾病杂志2016，Vol.19Issue(12)：8-10,3.
脑梗死患者血清超敏C反应蛋白D-二聚体含量及颈动脉粥样硬化斑块的测定及分析
Detection and analysis of levels of blood hs-CRP,D-Dimer and carotid atherosclerotic plaque in patients with acute cerebral infarction
杨华 1付家亮 1胡玉婷 1魏秀娥 1荣良群1
作者信息
- 1. 徐州医学院第二附属医院神经内科徐州 221006
- 折叠
摘要
Abstract
Objective To explore the changes and significances of levels of blood hs‐CRP ,D‐Dimer and carotid atheroscle‐rotic plaque in patients with acute cerebral infarction caused by internal carotid artery .Methods The levels of serum hs‐CRP and D‐Dimer in 85 patients who suffered from acute cerebral infarction for the first time were measured and were compared with that in normal controls .Carotid color ultrasonography was used to detect the carotid plaque .The relationships between the lev‐els of hs‐CRP ,D‐Dimer and carotid atherosclerotic plaque and NIHSS were analyzed .Results The blood levels of hs‐CRP ,D‐Di‐mer and the positive incidence of unstable plaque in patients with acute cerebral infarction were higher than that in the control group (all P< 0 .05);and patients with moderate‐heavy severity showed significantly higher levels and incidence than those with mild severity (all P<0 .05) .The levels of hs‐CRP and D‐Dimer in patients with unstable plaque were higher than that in patients without unstable plaque (P<0 .05) .The levels of both hs‐CRP and D‐Dimer were positively correlated with the NIH‐SS scores (r=0 .57 and 0 .38 ,respectively ,all P<0 .05) .Conclusion In order to predict and estimate the severity of acute cere‐bral infarction ,it is very valuable to observe the changes of levels of blood hs‐CRP ,D‐Dimer and the positive incidence of unsta‐ble plaque which are significantly increased in patients with acute cerebral infarction .关键词
脑梗死/超敏C反应蛋白/D-二聚体/不稳定斑块Key words
Cerebral infarction/Hypersensitive C-reactive protein/D-Dimer/Unstable plaque分类
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杨华,付家亮,胡玉婷,魏秀娥,荣良群..脑梗死患者血清超敏C反应蛋白D-二聚体含量及颈动脉粥样硬化斑块的测定及分析[J].中国实用神经疾病杂志,2016,19(12):8-10,3.
