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SAHA、 TRAIL与乳腺癌细胞凋亡

李静 周伟强

沈阳医学院学报2016,Vol.18Issue(3):183-186,4.
沈阳医学院学报2016,Vol.18Issue(3):183-186,4.DOI:10.16753/j.cnki.1008-2344.2016.03.019

SAHA、 TRAIL与乳腺癌细胞凋亡

SAHA, TRAIL and Apoptosis in Breast Cancer

李静 1周伟强2

作者信息

  • 1. 沈阳医学院基础医学院2014级研究生1班,辽宁 沈阳 110034
  • 2. 沈阳医学院基础医学院
  • 折叠

摘要

Abstract

Breast cancer is becoming as the most common malignant tumor that affects women�s health in the world. Numerous stud⁃ies have shown that histone deacetylase inhibitor SAHA and tumor necrosis factor⁃related apoptosis⁃inducing ligand ( TRAIL) can in⁃duce apoptosis in breast cancer cells, and the combination of TRAIL and SAHA has a synergistic effect, it can significantly enhance the breast cancer cells sensitivity to TRAIL treatment, so the strategy of SAHA and TRAIL treatment on breast cancer has become a welcome and promising method of clinical therapy.

关键词

SAHA/TRAIL/乳腺癌/细胞凋亡

Key words

SAHA/TRAIL/breast cancer/apoptosis

分类

医药卫生

引用本文复制引用

李静,周伟强..SAHA、 TRAIL与乳腺癌细胞凋亡[J].沈阳医学院学报,2016,18(3):183-186,4.

基金项目

国家自然科学基金项目 ()

沈阳医学院学报

1008-2344

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