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CCK-8人工神经修复大鼠坐骨神经长段缺损的实验研究

刘合庆 巩孝勇 郝鹏 李连亭

中国社区医师2016,Vol.32Issue(19):9-10,2.
中国社区医师2016,Vol.32Issue(19):9-10,2.DOI:10.3969/j.issn.1007-614x.2016.19.2

CCK-8人工神经修复大鼠坐骨神经长段缺损的实验研究

Experimental study on repairing sciatic nerve defect in rats with CCK-8 artificial nerve

刘合庆 1巩孝勇 2郝鹏 2李连亭2

作者信息

  • 1. 274009山东省菏泽市立医院脊柱外科
  • 2. 274000山东省曹县庄寨中心医院
  • 折叠

摘要

Abstract

Objective:To explore the effect of cholecystokinin-octopeptide on repairing defect of sciatic nerve.Methods:Wistar rats were divided into the A group and the B group.The A group were treated with CCK-8 injection,while the B group were injected with normal saline.Then we evaluated the degree of recovery after 12 weeks.Results:In the A group,the indexes in the seven indexes of motor behavior,the morphology of the regenerated nerve,the SFI% ,the NEP determination,the histological structure and the count and recovery rate of the pulp fibers were better than those of the B group,and the differences were statistically significant(P<0.05).Conclusion:CCK-8 can be used as artificial neural defect material in repairing long peripheral nerve.

关键词

八肽胆囊收缩素/坐骨神经/长段缺损/复合组织神经导管

Key words

Cholecystokinin-octopeptide/Sciatic nerve/Long defect/Composite tissue nerve conduit

引用本文复制引用

刘合庆,巩孝勇,郝鹏,李连亭..CCK-8人工神经修复大鼠坐骨神经长段缺损的实验研究[J].中国社区医师,2016,32(19):9-10,2.

中国社区医师

1007-614X

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