中国医学创新2016，Vol.13Issue(17)：37-40,4.DOI:10.3969/j.issn.1674-4985.2016.17.010
白癜风患者外周血中白介素25、白介素17、转化生长因子-β的表达及其临床意义
Clinical Significance and the Expression of Patients with Vitiligo in the Peripheral Blood Interleukin 25, Interleukin 17,Transforming Growth Factor-β
摘要
Abstract
Objective:To discuss the clinical significance and the expression of patients with vitiligo in the peripheral blood interleukin 25(IL-25),interleukin 17(IL-17),transforming growth factor-β(TGF-β).Method:A total of 120 patients with vitiligo were selected as vitiligo group,30 cases health person were selected as healthy group,enzyme-linked immunosorbent method was used to detect all the expression of IL-25,IL-17, TGF-β levels,Pearson correlation analysis was used to analyze the expression level of IL-25,IL-17,TGF-βand vitiligo skin damage area.Result:The vitiligo group expression level of IL-25,IL-17,TGF-β were higher than the healthy group(P<0.05).Pearson correlation analysis results showed that,the expression of IL-25 (r=0.683,P<0.05),IL-17(r=0.576,P<0.05),TGF-β(r=0.621,P<0.05) level were positively correlated with the damaged skin area.Conclusion:High expression of IL-25,IL-17,TGF-β May be associated with the development of vitiligo,and positively correlated relationship with the patient skin damage area,their expression level change state of patients.关键词
白癜风/IL-25/IL-17/TGF-β/皮肤受损面积Key words
Vitiligo/IL-25/IL-17/TGF-β/Damaged skin area引用本文复制引用
王鲁梅,卢婉娇,袁景桃,张斌,李俊杰..白癜风患者外周血中白介素25、白介素17、转化生长因子-β的表达及其临床意义[J].中国医学创新,2016,13(17):37-40,4.基金项目
东莞市科技计划医疗卫生类科研一般项目 （）
