中国医学创新2016，Vol.13Issue(17)：142-145,4.DOI:10.3969/j.issn.1674-4985.2016.17.041
野百合碱诱导肺动脉高压动物模型机制研究
The Mechanism Research of Pulmonary Hypertension Animal Model Induced by Monocrotaline
丘水林 1黄石安2
作者信息
- 1. 广东医学院 广东 湛江 524000
- 2. 广东医学院附属医院
- 折叠
摘要
Abstract
Pulmonary hypertension (PH) is characterized by remodeling of the pulmonary arterial vessels,which increases the pulmonary vascular resistance and right ventricular afterload, thus contributing to the development of right ventricle dysfunction and failure.The monocrotaline(MCT) rat model continues to be a frequently investigated model of PH,since it offers technical simplicity,reproducibility, and low cost compared with other models of PH.This article will define the specific process of PH rat model induced by MCT.Whether this model simulations plexiform vascular lesions of patients with PH.关键词
肺动脉高压/野百合碱/大鼠模型Key words
Pulmonary hypertension/Monocrotaline/Rat model引用本文复制引用
丘水林,黄石安..野百合碱诱导肺动脉高压动物模型机制研究[J].中国医学创新,2016,13(17):142-145,4.
