中国医学创新2016，Vol.13Issue(18)：34-36,3.DOI:10.3969/j.issn.1674-4985.2016.18.010
80例原发性肾病综合征合并甲状腺功能减退的临床和病理分析
Clinical and Pathological Analysis for 80 Cases of Primary Nephrotic Syndrome Complicating with Hypothyroidism
摘要
Abstract
Objective: To discuss the clinical significance of 80 patients’clinical characteristics and pathological types who have primary nephrotic syndrome complicating with hypothyroidism.Method:80 patients of primary nephrotic syndrome complicating with hypothyroidism in our hospital were selected,they all received kidney biopsy and thyroid function test(TT3,TT4,FT3,FT4 and TSH),plasma albumin,24 hours urine protein quantitative and so on,and then the pathological types and clinical characteristics were analyzed.Result:The pathological types were membranous glomerulonephritis (MGN) of 43 cases, minimal change disease (MCD) of 29 cases, mesangial proliferative glomerulonephritis (MSPGN) of 4 cases,focal segmental glomerulosclerosis (FSGS) of 2 cases, and membranoproliferative glomerulonephritis (MPGN) of 2 cases. For patients with primary nephrotic syndrome,their serum albumin had positive correlation with serum TT3, FT3,TT4,FT4, and had negative correlation with serum TSH;24 hours urine protein quantitative had negative correlation with serum TT3,FT3,TT4,FT4,and had no obvious correlation with serum TSH.Conclusion:For patients of primary nephrotic syndrome complicating with hypothyroidism,the pathological types are membranous glomerulonephritis and minimal change disease as the common.The level of thyroxin and albumin decrease have a close correlation.So, the test for thyroxin has an important reference value to judge the lesion degree,prognosis and pathological types for patients with primary nephrotic syndrome complicating with hypothyroidism.关键词
原发性肾病综合征/甲状腺功能减退/临床特点/病理类型Key words
Primary nephrotic syndrome/Hypothyroidism/Clinical characteristics/Pathological types引用本文复制引用
陈晓风,李晶,谷小丽,王攀..80例原发性肾病综合征合并甲状腺功能减退的临床和病理分析[J].中国医学创新,2016,13(18):34-36,3.基金项目
河北省中医药管理局中医类科研计划课题项目 （）
