北京中医药大学学报2016，Vol.39Issue(5)：376-382,7.DOI:10.3969/j.issn.1006-2157.2016.05.006
应用文献挖掘及关联规则分析方法挖掘分析古代方剂中粪便类中药的基本特征及其应用∗
Literature study on fecal class Chinese medicines and their application in the ancient prescriptions
摘要
Abstract
Objective To summarize the basic characteristics of fecal class Chinese medicines in modern clinical practice, and to find out the application of them in ancient prescriptions. Methods Taking“fe-ces”(Chinese:粪便;pinyin:fènbiàn) and “Chinese medicines”(Chinese: 中药; pinyin: zhōngyào) as the keywords, we searched CNKI, Wangfang, CQVIP and CBM databases of relevant articles pub-lished since the time of establishment. Then the fecal class Chinese medicines were screened. What we obtained were where the official names came from, what their alternative names were at different times, which creatures they were excreted from, what property and flavor, meridian tropism, efficacy and indi-cations they had. Furthermore, we searched the ancient prescriptions involving fecal class Chinese medi-cines using the database platform of Dictionary of Chinese Medicine Prescriptions, institute of Chinese Materia Medical of China Academy of Chinese Medical Sciences to get the common compatibility and po-tential rules of clinical application. Results Total eleven fecal class Chinese were common used in mod-ern clinical practice, which were recorded in various monographs of Chinese medicine by numerous names, and were excreted from birds, mammals and worm. The nature of the medicines were hot or cold;the flavor coved sour, bitter, sweet, bitter, salty; the meridian tropism lied in meridian of liver ( gall bladder) ,heart ( cardiac ) , spleen ( stomach ) , lung ( intestine ) and kidney ( bladder ); the various effects were listed as the following: resolving superficies, clearing heat, dispelling pathogenic wind and removing dampness, resolving stagnation, expelling blood stasisfor removing obstruction in collaterals, re-moving phlegm, relieving cough, calming endogenous wind, inducing resuscitation, removing toxicity, destroying parasites, relieve itching, eliminating necrotic tissues and promoting granulation. In addition, we extracted relevant 1 550 relevant prescriptions containing the eleven medicines which had the internal pharmaceutical compatibility and association rules. Conclusion The application of fecal class Chinese medicines has a long history. The further study and innovating application will be much of value of re-search and application in the intestinal microecology and the diagnosis and treatment of various diseases.关键词
中药/方剂/肠道菌群/粪便移植Key words
traditional Chinese medicine/prescription/intestinal flora/fecal microbiota transplantation分类
医药卫生引用本文复制引用
苏泽琦,张文君,张雨珊,王德辰,孟祥梅,王玮鑫,吴嘉瑞,李健,丁霞..应用文献挖掘及关联规则分析方法挖掘分析古代方剂中粪便类中药的基本特征及其应用∗[J].北京中医药大学学报,2016,39(5):376-382,7.基金项目
国家自然科学基金面上项目(No.81270466),教育部高等学校博士学科点专项科研基金(No.20120013110014) （No.81270466）
