北京中医药大学学报2016，Vol.39Issue(5)：424-428,5.DOI:10.3969/j.issn.1006-2157.2016.05.014
慢性阻塞性肺疾病肺气虚证肺容积成像定量分析与症状积分分级的研究∗
Quantitative analysis of CT images on lung volume, rating and integral on symptoms：a study on chronic obstructive pulmonary disease patients with syndrome of lung-qi deficiency
摘要
Abstract
Objective To combine the functional quantitative indicators with the morphological imaging diagnosis by quantitative CT on chronic obstructive pulmonary disease ( COPD) patients, so as to provide the objective and quantitative indicators for TCM differentiation and for degrees of lung parenchyma inju-ry. Methods A total of 75 COPD patients at stable stage with syndrome of lung-qi deficiency were di-vided into three groups ( mild, moderate, severe) in accordance with Clinical Guideline of New Drug for Traditional Chinese Medicine, and 20 more healthy people were recruited into healthy group. After lung CT scan, the multi-range imaging quantitative analysis was carried using the post-proceeding three-dimen-sion technology. Then the CT quantitative indicators and the integral and rating of symptoms of patients were compared with the healthy subjects. Results Compared with the healthy group,the mean volume of each lung lobe, and proportion of emphysema volume increased in all three COPD groups. Furthermore,the more serious the symptoms were, the larger volumes of lung lobes and the more proportion of emphy-sema volume were. The proportion of emphysema volume in upper lobes or in right middle lobe were lar-ger. Conclusion The correlation between the volume of lung lobes and emphysema and the degrees of integral of TCM symptoms were proved. And the introduction of the quantitative indicators could increase the objectivity and reliability of TCM treatment on COPD.关键词
慢性阻塞性肺疾病/肺容积/症状积分/CT技术Key words
chronic obstructive pulmonary disease/lung volume/integral of symptoms/CT technology分类
医药卫生引用本文复制引用
彭楠,路遥,赵晶,康德强,郭红丽..慢性阻塞性肺疾病肺气虚证肺容积成像定量分析与症状积分分级的研究∗[J].北京中医药大学学报,2016,39(5):424-428,5.基金项目
北京中医药大学临床自主创新课题(No.2011jybzzjsy-096) （No.2011jybzzjsy-096）
