长春中医药大学学报2016，Vol.32Issue(3)：504-505,2.DOI:10.13463/j.cnki.cczyy.2016.03.023
参附注射液对急性左心功能不全患者心功能及血浆脑钠肽的影响
Shenfu injection on cardiac function and brain natriuretic peptide in patients with acute left heart failure
摘要
Abstract
Objective To explore the effect of Shenfu injection on the cardiac function and brain natriuretic pep-tide(BNP)in patients with acute left heart failure(AHF). Methods A total of 60 AHF patients were randomized into the observation group and the control group with each group 30. The patients in the two groups were given corre-sponding oxygen inhalation,bed rest,low-salt diet,furosemide,20 mg / time,1time / d,IVP;nitroglycerin(10 mg) +0. 9% sodium chloride(250mL),continuous pumping,1time / d;digoxin,0125mg / time,1time / d. On this basis,the patients in the observation group were given additional Shenfu injection(60 mL) + 0. 9% sodium chloride(250 mL),ivgtt,1time / d. Seven-day treatment was regarded as one course. Chemiluminescence immunoassay was used to detect the plasma BNP level before and after treatment. The echocardiography was used to determine LVEDD. LVEF was calculated. Guyatt was used for six minute walk test(6MWT). The maximum 6 min walking distance was deter-mined. Results BNP level after treatment was significantly reduced,and the reduced degree in the observation group was significantly superior to that in the control group(P < 0. 05). LVEDD after treatment was significantly decreased, but LVEF and 6MWT were significantly increased,those in the observation group were significantly superior to those in the control group(P < 0. 05). Conclusion Shenfu injection can enhance the left ventricular systolic function,effec-tively reduce the plasma BNP level,and improve the cardiac function with a satisfying effect.关键词
参附注射液/急性左心功能不全/心功能/血浆脑钠肽Key words
Shenfu injection/AHF/cardiac function/plasma BNP分类
医药卫生引用本文复制引用
张志林,温玉梅..参附注射液对急性左心功能不全患者心功能及血浆脑钠肽的影响[J].长春中医药大学学报,2016,32(3):504-505,2.基金项目
河北省张家口市科技计划项目（0801043D）。 （）
