磁共振成像2016，Vol.7Issue(5)：332-336,5.DOI:10.12015/issn.1674-8034.2016.05.003
MR扩散张量成像定量参数FA和ADC值在前列腺移行带结节良恶性分级中的应用价值
Feasibility study of FA and ADC values by diffusion tensor imaging：classify abnormal signal nodules in prostate transition zone
摘要
Abstract
Objective: To investigate the diagnostic utility of FA (fractional anisotropy) and ADC (apparent diffusion coefficient) values of diffusion tensor imaging (DTI) in classifying abnormal signal nodules in prostate transition zone (TZ). Materials and Methods: Fifty-four TZ-PCa cases and thirty BPH cases with pathologically confirmed were enrolled in this retrospective study. All the patients were divided into 3 groups: BPH, Gleason score (GS)≤3+4=7, GS≥4+3=7, and underwent with 3.0 T MRI. The FA and ADC values of the region of interest (ROI) were respectively measured, using one-way ANOVA to compare the difference between groups. Results: The mean FA values of the 3 groups were 150.52±29.63, 215.21±54.59, 251.01±59.47, respectively, and there was statistical difference between the groups (F=32.882, P=0.000). Comparison among groups: just BPH with the other two groups had statistical difference (P=0.000, P=0.000). The mean ADC values (×10–6 mm2/s) of the 3 groups were 1606.11±234.64, 854.00±172.29, 742.78±115.91, respectively, and there was statistical difference between the groups (F=202.928, P=0.000). Comparison among groups: BPH with the other two groups had statistical difference (P=0.000, P=0.000). GS≤3+4=7 and GS≥4+3=7 had statistical difference (P=0.040). Conclusions: The FA and ADC values of DTI have higher value for distinguishing benign and malignant nodules. ADC values has obvious advantages than FA in the further classification.关键词
前列腺肿瘤/弥散张量成像Key words
Prostatic neoplasms/Diffusion tensor imaging分类
医药卫生引用本文复制引用
可赞,王良,邓明,闵祥德,蔡杰,冯朝燕,李拔森..MR扩散张量成像定量参数FA和ADC值在前列腺移行带结节良恶性分级中的应用价值[J].磁共振成像,2016,7(5):332-336,5.基金项目
国家自然科学基金面上项目(编号81171307)ACKNOWLEDGMENTS This work was part of project of the National Natural Science Foundation of China (No.81171307) （编号81171307）
