磁共振成像2016，Vol.7Issue(5)：365-370,6.DOI:10.12015/issn.1674-8034.2016.05.009
脑实质囊虫病亚临床期的1H-MRS成像研究
1H magnetic resonance spectroscopy studies on subclinical neurocysticercosis
摘要
Abstract
Objective: To evaluate the clinical application of single voxel 1H magnetic resonance spectroscopy in diagnosis of subclinical neurocysticercosis. Materials and Methods: One hundred and ten cases of subclinical neurocysticercosis and 130 cases of cerebral cysticercosis (live worms stage) with contrast enhanced single voxel 1H magnetic resonance spectroscopy were screened for this study. Observation of the change in ratio of the lesions of the subclinical neurocysticercosis and some trace metabolites around the lesions was done. Results: The group of subclinical neurocysticercosis has no significant difference with normal control group in various biochemical metabolites. The ratios of NAA/Cho, Cho/Cr and Lip/Cr have statistical significance in the analysis and evaluation of subclinical neurocysticercosis group and live worms stage group. The ratio of NAA/Cho in subclinical neurocysticercosis group is higher than live worms stage group. The ratios of Cho/Cr and Lip/Cr of the former are lower than that of the latter. The ratios of NAA/Cho and Lip/Cr evaluate the differential diagnosis efficiency between subclinical neurocysticercosis stage and live worms stage on ROC curve. Conclusions: 1H-MRS reveals the changes in characteristics of subclinical neurocysticercosis stage and live worms stage so as to evaluate the corresponding diagnosis index of the ratios of NAA/Cho and Lip/Cr, which are of great value to early diagnosis and treatment of the neurocysticercosis.关键词
神经系统囊虫病/脑疾病/磁共振波谱学Key words
Neurocysticercosis/Brain diseases/Magnetic resonance spectroscopy分类
医药卫生引用本文复制引用
王青,张承志,李信响,徐鲲,苏洁..脑实质囊虫病亚临床期的1H-MRS成像研究[J].磁共振成像,2016,7(5):365-370,6.基金项目
国家自然科学基金(编号81060225)ACKNOWLEDGMENTS This study was supported by Grants the National Natural Science Foundation of China (No.81060225) （编号81060225）
