分析化学2016，Vol.44Issue(6)：984-993,10.DOI:10.11895/j.issn.0253-3820.150971
磷脂组学研究中的分析检测技术
Advance in Analysis and Detection Technologies for Phospholipidomics
摘要
Abstract
Phospholipids, the principal constituents of cell membranes, have very important physiological functions and is closely related to human health and diseases. Therefore, comprehensive analysis of phospholipids is essential to enhance our understanding of function of phospholipids in disease process. Phospholipidomics is a phospholipids-targeted metabolomic approach which focuses on comprehensive qualitation and quantitation of phospholipids in biological system. Phospholipidomics study is carried out by the analysis and detection technologies involved in sample preparation, separation, qualitation and quantitation and data mining. In this paper, analysis and detection technologies for phospholipidomics are reviewed, providing a valuable reference for developing fast, stable, reliable, high sensitivity, high resolution, and high throughput platform technologies for phospholipidomics. The integrated investigation of phospholipidomics and other omics are proposed to promote the further development of analytical bioscience.关键词
磷脂/分析检测技术/磷脂组学/综述Key words
Phospholipids/Analysis and detection technologies/Phospholipidomics/Review引用本文复制引用
朱超,梁琼麟,王义明,罗国安,Rob J. Vreeken,Thomas Hankemeier..磷脂组学研究中的分析检测技术[J].分析化学,2016,44(6):984-993,10.基金项目
本文系国家自然科学基金项目(Nos.81202502,81130066,81230079)资助This work was supported by the National Natural Science Foundation of China (Nos.81202502,81130066,81230079) （Nos.81202502,81130066,81230079）
