长链非编码RNA调控肿瘤细胞凋亡的研究进展OACSTPCD
Progress of long non-coding RNA in regulating apoptosis of tumor cells
长链非编码RNA(long non-coding RNA，lncRNA)是一类长度>200个核苷酸、通常不编码蛋白质的RNA。近年研究表明，lncRNA在肿瘤的的发展过程中发挥抑癌或促癌作用，参与细胞增殖、凋亡等过程。本综述简要介绍lncRNA的生物学功能及其调控细胞凋亡的研究进展。
Long non-coding RNA is a kind of RNA that is more than 200 nucleotides in transcript length and non-protein coding RNA. In the recent years, data have shown that lncRNA plays an important role in the development of tumor by suppressing or promoting cancer, and involves in regulating cell apoptosis and proliferation. hTis review brielfy introduces the function of lncRNA, and summarizes progress of lncRNA in regulating apoptosis of tumor cells.
梁亚雪(综述);唐圣松(审校)
南华大学药物药理研究所，湖南 衡阳 421001南华大学药物药理研究所，湖南 衡阳 421001
长链非编码RNA细胞凋亡肿瘤
long non-coding RNAapoptosistumor
《临床与病理杂志》 2016 (5)
675-680,6
湖南省高校科技创新平台开放基金(09K072，12K120)。@@@@This work was supported by Open Fund of Science and Technology Innovation Platform in Hunan Province (09k072,12k120), P. R. China
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