海南医学院学报2016，Vol.22Issue(14)：1584-1586,1590,4.DOI:10.13210/j.cnki.jhmu.20160414.012
吲哚菁绿联合亚甲蓝在乳腺癌前哨淋巴结活检术中的应用研究
Appl ication of Indocyanine green joint methylene blue for sentinel lymph node biophy in pa-tients with breast cancer
摘要
Abstract
Objective:To discuss the value of Indocyanine green joint methylene blue in sentinel lymph node biophy for patients with breast cancer.Methods:A total of 200breast cancer patients were selected and randomly divided into test group and control group,with 100 cases in eachgroup.The test group received indocyanine green and methylene blue as the lymphatic mapping tracers and the control group received methylene blue only.Intraoperative frozen section was performed followed by conventional histopathology.Results:The positive rate,sensitivity,false negative rate,consistent rate and the Kappa values of the test group were 98.00% (98/100),95.74% (45/47),4.26% (2/47),96.94% (95/98)and 0.860,the corresponding data for the control group was 94.00% (94/100)and 86.96% (40/46),13.04% (6/46),93.62% (88/94)and 0.758 showing sig-nificant difference in positive rate,sensitivity,false negative rate,consistent rate and the Kappa values between the two groups (P <0.05 ).Conclusion:With advantages of real-time visual and accurate positioning,Indocyanine green joint methylene blue shows high positive rate,accuracy and low fake negative rate when it is used for sentinel lymph node biophy in patients with breast cancer.关键词
乳腺癌/前哨淋巴结活组织检查/吲哚菁绿Key words
Breast cancer/Sentinel lymph node biopsy/Indocyanine green分类
医药卫生引用本文复制引用
崔仁忠,杨接辉,潘承欣..吲哚菁绿联合亚甲蓝在乳腺癌前哨淋巴结活检术中的应用研究[J].海南医学院学报,2016,22(14):1584-1586,1590,4.基金项目
中山市博爱医院医学科研基金项目(2015A020001)[Foundation Project]:This study was supported by medicalresearch foundation ofBoai Hospital of ZhongshanCity (grant No ．2015 A020001) （2015A020001）
