海南医学院学报2016，Vol.22Issue(14)：1601-1603,3.DOI:10.13210/j.cnki.jhmu.20160415.002
苦参注射液联合延续护理对膀胱癌术后膀胱灌注化疗患者疗效的影响
Effect of Kushen injection in combined with continuing nursing on the patients with instillation therapy after bladder cancer surgery
摘要
Abstract
Objective:To observe the effect of Kushen injection in combined with continuing nursing on the patients with instillation therapy after bladder cancer surgery.Methods:A total of 60 patients with bladder cancer who were admitted in our hospital were included and randomized into the observation group and the control group.The patients in the two groups were given routine THP instillation therapy.On this basis,the patients in the observation group were given additional Kushen injection in combined with continuing nursing.The occurrence rate of adverse reactions during the chemotherapy period and the improvement of immunological indicators in the two groups were compared.SF-36 health survey scale was used to evaluate pa-tients’life quality.Results:After treatment,CD4 + and NK cell level in the observation group were significantly elevated (P <0.05),but CD8 + level was significantly reduced when compared with that before treatment (P <0.05).CD4 + ,CD8 + ,and NK cell levels in the control group were not significantly different from those before treatment (P >0.05 ).The bladder irritation symptoms during the chemotherapy period in the observation group were significantly lighter than those in the control group (P <0.05).The occurrence rate of main adverse reactions during the chemotherapy period in the observation group was signifi-cantly less than that in the control group (P <0.05).The lifequality scores in the observation group were significantly higher than those in the control group (P <0.05).Conclusions:Kushen injection in combined with continuing nursing can effectively regulate the immunological function in patients with instillation therapy after undergoing bladder cancer surgery,it could reduce the occurrence rate of adverse reactions,and enhance patients’life quality.关键词
苦参注射液/延续护理/膀胱癌/膀胱灌注化疗/免疫功能/生活质量Key words
Kushen injection/Continuing nursing/Bladder cancer/Instillation therapy/Immunological function/Life quality分类
医药卫生引用本文复制引用
韩瑞霞,韩瑞敏,陈立坤,刘明娟,都海明,唐志前,耿连霞..苦参注射液联合延续护理对膀胱癌术后膀胱灌注化疗患者疗效的影响[J].海南医学院学报,2016,22(14):1601-1603,3.基金项目
河北省卫计委科研项目(20150090)[Foundation Project]:The study was supported by the Scientific and Research Project of Health Planning Commission in Hebei Province with the number of 20150090． （20150090）
