口腔颌面外科杂志2016，Vol.26Issue(2)：140-144,5.DOI:10.3969/j.issn.1005-4979.2016.02.014
长链非编码RNA及其在自身免疫性疾病发生发展中的作用
Recent Advances on Long Noncoding RNA and the Autoimmune Diseases
陈婵 1石欢(综述) 1郑凌艳(审校)1
作者信息
- 1. 上海交通大学医学院附属第九人民医院·口腔医学院口腔颌面外科，上海 200011
- 折叠
摘要
Abstract
Long non-coding RNA (lncRNAs) is a functional non-protein-coding class whose length is longer than 200 nucleotides. Recent studies have demonstrated that a series of patterns including epigenetic modification and protein modification,regulation of target gene expression,and transcription intervention are involved in this process. The lncRNAs play crucial role in differentiation and activation of immune cells, and its relationship with human autoimmune diseases has been given more and more attention. With the development of microarray, many of the potential function of lncRNA have been discovered gradually. This article reviews recent research advances in this aspect with an attempt to better understand the role of LncRNA in autoimmune diseases .关键词
长链非编码RNA/自身免疫性疾病/基因芯片技术Key words
long noncoding RNA/autoimmune disease/microarray分类
医药卫生引用本文复制引用
陈婵,石欢(综述),郑凌艳(审校)..长链非编码RNA及其在自身免疫性疾病发生发展中的作用[J].口腔颌面外科杂志,2016,26(2):140-144,5.
