中国临床保健杂志2016，Vol.19Issue(3)：228-231,4.DOI:10.3969/J.issn.1672-6790.2016.03.002
多发性骨髓瘤免疫表型特征及其临床意义
Immunophenotype and its clinical significant of multiple myeloma
摘要
Abstract
Objective To explore the immunophenotype and its clinical significant of Multiple Myeloma (MM).Methods The immunophenotype of 40 patients with MMand 20 normal volunteers were detected by multipa-rameter flow cytometry(MP-FCM).Results The abnormality expression of antigens sequence of patients with MMwas CD45 dim +/-(95%),CD81 dim +/-(80%),CD56 + (70%),CD27 dim +/-(50%),CD200 ++ (48%),CD33 + (40%), CD28 ++(35%),CD117 +(18%),CD19 +(5%),CD20 +(3%)in order.However the positive rations of CD56 +, CD200dim +and CD28dim + were 10%,10%and 5%,respectively.Conclusion MP-FCM inspections can accurately discriminate the benign and malignant plasma cell,and provide evidence for prognosis evaluation and targeted therapy.关键词
多发性骨髓瘤/免疫表型分型/浆细胞/流式细胞术Key words
Multiple myeloma/Immunophenotyping/Plasma Cells/Flow cytometry分类
医药卫生引用本文复制引用
张翠萍,汪鹏,李庆,徐修才,胡超杰,郑南..多发性骨髓瘤免疫表型特征及其临床意义[J].中国临床保健杂志,2016,19(3):228-231,4.基金项目
国家自然科学基金面上项目（81472018）；安徽省自然科学基金面上项目 （）
