中国临床保健杂志2016，Vol.19Issue(3)：315-319,5.DOI:10.3969/J.issn.1672-6790.2016.03.031
中医药对血管新生相关信号通路的影响
Effects of traditional Chinese medicine on angiogenesis related signaling pathway
摘要
Abstract
Angiogenesis is a common and important process of physiological and pathological.The process in-volves a lot of cells,cytokines and related signaling pathways.The development of many diseases are closely related to angiogenesis.Cytokines can affect angiogenesis by signaling pathways to mediate migration,proliferation,apoptosis of an-giogenesis-related cell.In recent years,new research about mechanism of angiogenesis shows that VEGF pathway,Notch pathway,PTEN /PI3K/AKTpathway,JAK/STAT pathway involved in regulating angiogenesis.Chinese medicine can be regulating angiogenesis by adjusting signal transduction pathways,and had made certain achievements in the treatment of angiogenesis-based diseases.关键词
血管生成调节剂/新生血管化,生理性/信号传导/中草药Key words
Angiogenesis modulating agents/Neovascularization,physiologic/Signal transduction/Drugs,Chi-nese herbal分类
医药卫生引用本文复制引用
刘磊,刘健,万磊,纵瑞凯,曹云祥..中医药对血管新生相关信号通路的影响[J].中国临床保健杂志,2016,19(3):315-319,5.基金项目
国家临床重点专科中医风湿病科建设项目（财社［2013］239号）；国家中医药重点学科中医痹病学建设项目（国中医药发［2009］30号）；“十二五”国家科技支撑计划项目（2012BAI26B02）；安徽省重点实验室建设项目（1306c083035）；安徽省科技计划项目 （）
