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复合中药提取物对人皮肤成纤维细胞线粒体膜电位的影响

邓小锋 孟宏 李丽 时宇静

日用化学工业2016,Vol.46Issue(5):289-291,3.
日用化学工业2016,Vol.46Issue(5):289-291,3.DOI:10.13218/j.cnki.csdc.2016.05.010

复合中药提取物对人皮肤成纤维细胞线粒体膜电位的影响

Effect of blended herb extract on mitochondrial membrane potential of fibroblast

邓小锋 1孟宏 1李丽 1时宇静2

作者信息

  • 1. 北京工商大学,北京 100048
  • 2. 中国中医科学院中药研究所,北京 100700
  • 折叠

摘要

Abstract

Apoptosis state of fibroblast of adult skin can be reflected by mitochondrial membrane potential to a certain extent. Experimental results showed that,as comparing with result obtained in the normal control group, that in the hydrogen peroxide group shows reduction of the skin fibroblast mitochondrial membrane potential (P<0.01 );while in the model groups with additive composed of extract of blended herb with separate dosages of 75,150 and 300 mg/L,their mitochondrial membrane potential of skin fibroblast are significantly increased (P<0.01),and shows a dose-dependent manner. Such experimental result indicated that the blended herb extract is effective for prevention of mitochondrial membrane potential decreasing caused by hydrogen peroxide and can be used for delaying of skin senility as a prophylactic measure. Hopefully,the blended herb extract may be used as an additive in cosmetics.

关键词

化妆品添加剂/复合中药提取物/线粒体膜电位

Key words

cosmetic additives/blended herb extract/mitochondrial membrane potential

分类

化学化工

引用本文复制引用

邓小锋,孟宏,李丽,时宇静..复合中药提取物对人皮肤成纤维细胞线粒体膜电位的影响[J].日用化学工业,2016,46(5):289-291,3.

基金项目

北京市优秀人才培养资助D类(2014000020124G034);北京工商大学化妆品协同创新中心资助项目(19005428069/007);2015年研究生科研能力提升计划项目资助 ()

日用化学工业

OA北大核心CSCDCSTPCD

1001-1803

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