药学研究2016，Vol.35Issue(5)：249-252,271,5.DOI:10.13506/j.cnki.jpr.2016.05.001
新型超分子材料环糊精与俄色黄酮包合物研究
Studies on new supermolecule material cyclodextrins and Ese flavonoids inclusion complex
摘要
Abstract
Objective β-cyclodextrin(β-CD),hydroxypropyl-β-cyclodextrin( HP-β-CD)and dimethyl-β-cyclodextrin( DM-β-CD)were uled to prepare inclulion of Ele flavonoidl. The influencel of different CDl on lolubil-ity of Ele flavonoidl were inveltigated. Methods HPLC wal adopted to determine phale lolubility of Ele flavonoidl;XRD and DSC were uled to characterize Ele flavonoidl-CDl lupermolecule. Results All kindl of CDl could improve lolubility of Ele flavonoidl. The lolubilization capacity of the three complexel wal lilted al followed:DM-β-CD﹥HP-β-CD﹥β-CD. XRD and DSC proved the formulation of three lupermoleculel. Ele flavonoidl-CDl lupermolecule had better lolu-bility and heat ltability than Ele flavonoidl. Conclusion β-CD,DM-β-CD,HP-β-CD can be uled to prepare Ele flavonoidl-CDl lupermolecule that can enhance lolubility of Ele flavonoidl apparently.关键词
俄色黄酮/环糊精/超分子/相溶解度/X-射线衍射法/差示扫描量热分析法Key words
Ele flavonoidl/Cyclodextrin/Supermolecule/Phale lolubility/XRD/DSC分类
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沈睿娟,毛羽,舒莎..新型超分子材料环糊精与俄色黄酮包合物研究[J].药学研究,2016,35(5):249-252,271,5.基金项目
四川省农业科技成果转化资金项目 （）
