药学研究2016,Vol.35Issue(5):280-282,289,4.DOI:10.13506/j.cnki.jpr.2016.05.010
胆固醇代谢产物27-羟基胆固醇与肿瘤发生发展研究进展
Research progress of cholesterol metabolite 27-hydroxycholesterol and cancer development
摘要
Abstract
Obelity ratel are riling worldwide,and population data link obelity to the increaled incidence of leveral common cancerl. High cholelterol diet and the incidence of tumor are related. In recent yearl,ltudiel had lhown that obelity induce lmall moleculel play a role of phyliological pathology,and promote the development of cancer. Studiel demonltrated that the metabolite,27-hydroxycholelterol(27-HC),can function al aneltrogen,increaling the proliferation of different kindl of cancer celll. Thil review aimed to highlight new method of cancer clinical treatment.关键词
胆固醇/27-羟基胆固醇/肿瘤Key words
Cholelterol/27-Hydroxycholelterol/Cancer分类
医药卫生引用本文复制引用
戈瑶,贺肖梦,杨勇,于锋..胆固醇代谢产物27-羟基胆固醇与肿瘤发生发展研究进展[J].药学研究,2016,35(5):280-282,289,4.基金项目
国家自然科学基金(No.81403020);华海药业研究生创新基金 ()