上海针灸杂志2016，Vol.35Issue(6)：732-737,6.DOI:10.13460/j.issn.1005-0957.2016.06.0732
电针对急性心肌缺血损伤大鼠相关经穴皮肤血流灌注量影响的后效应研究
Study of the Post Effect of Electroacupuncture on Blood Flow in the Skins of Related Meridian Points in Rats with Acute Ischemic Myocardial Injury
摘要
Abstract
Objective To observe over-time changes in rat blood flow in the skins of related meridian points during physiological status, the pathological state of ischemic myocardial injury and low or high frequency electroacupuncture intervention and explore the post effect of different frequency electroacupuncture on related meridian points after treating ischemic myocardial injury. Method Fifty male Wister rats were randomized into five groups: blank control, sham operation, model, low frequency electroacupuncture (meridian point A) and high frequency electroacupuncture (meridian point B), 10 rats each. Blood flow in the skins of bilateral points Neiguan (PC6), Ximen (PC4) and Tianquan (PC2), and non-meridian and non-acupoint control points was measured by laser speckle contrast imaging in every group immediately and at 30 and 60 min after the end of three treatments. Statistical analysis was made. Result Blood flow in the skins of bilateral points Neiguan, Ximen and Tianquan was significantly lower in the blank control group than in the model group (P<0.01,P<0.05). Blood flow in the skin of every acupoint increased in varing degrees after low or high frequency electroacupuncture treatment. Blood flow in bilateral points Neiguan, Ximen and Tianquan regions in meridian point group A was closer to that in the blank control group immediately after treatment. Blood flow in three left-side and three right-side acupoint regions in meridian point group B was closer to that in the blank control group at 30 and 60 min, respectively, after treatment. Conclusion The immediate effect of low frequency electroacupuncture on blood flow in acupoint regions is better than high frequency electroacupuncture during intervention in ischemic myocardial injury. The post effect of high frequency electroacupuncture on blood flow in acupoint regions is better than low frequency electroacupuncture during intervention in ischemic myocardial injury.关键词
心肌缺血损伤/电针/皮肤血流灌注量/针灸后效应/大鼠Key words
Ischemic myocardial injury/Electroacupuncture/Dermal blood flow/Acupuncture post effect/Rats分类
医药卫生引用本文复制引用
刘亚利,毛颖秋,孙晓敏,白红新,许咏思,赵国桢,张平,嵇波,戴健,路雅雯,严明娜,王丹,郭孟玮..电针对急性心肌缺血损伤大鼠相关经穴皮肤血流灌注量影响的后效应研究[J].上海针灸杂志,2016,35(6):732-737,6.基金项目
国家自然科学基金面上项目(81373558) （81373558）
