天津中医药2016，Vol.33Issue(5)：260-264,5.DOI:10.11656/j.issn.1672-1519.2016.05.02
针刺阳陵泉对中风偏瘫患者感觉运动网络影响的fMRI研究
A functional magnetic resonance imaging (fMRI) study on the effect of acupuncture at GB34 (Yanglingquan) on sensorimotor network in stroke patients with hemiplegia
摘要
Abstract
[Objective] To observe the characteristic of brain functional regions of the effect of acupuncture at Yanglingquan (GB34) on sensorimotor network of stroke patients with hemiplegia, and investigate the effect mechanism of acupuncture at Yanglingquan (GB34) on promoting brain reorganization of stroke patients with hemiplegia. [Methods] 12 stroke patients with hemiplegia and 8 healthy controls in accordance with the inclusive criteria were recruited and underwent resting state fMRI scanning before and after acupuncture stimulation, the method of generalized linear models was used to analyze the components of sensorimotor network extracted from all the subjects and compare the brain regions activated by acupuncturing at Yanglingquan (GB34). [Results] Compared with healthy controls, acupuncture at Yanglingquan (GB34) showed positive effect at right cingulate gyrus, right superior frontal gyrus, right medial frontal gyrus, right lingual gyrus, right declive, left precuneus and left superior parietal lobule, while negative effect mainly occurred at left anterior cingulate gyrus, left superior frontal gyrus, right superior frontal gyrus, left middle frontal gyrus, left inferior frontal gyrus, left medial frontal gyrus, right medial frontal gyrus, left superior temporal gyrus, left cuneus, and left precuneus. [Conclusion] Acupuncture at Yanglingquan (GB34) may promote the brain reorganization of stroke patients with hemiplegia by modulating some brain regions activity related to the sensorimotor network of the bilateral cerebral hemisphere and enhancing the effect of sensory feedback on motion output.关键词
中风/偏瘫/针刺/阳陵泉/感觉运动网络/功能磁共振Key words
stroke/hemiplegia/acupuncture/Yanglingquan/sensorimotor network/fMRI分类
医药卫生引用本文复制引用
付彩红,李匡时,邹忆怀..针刺阳陵泉对中风偏瘫患者感觉运动网络影响的fMRI研究[J].天津中医药,2016,33(5):260-264,5.基金项目
国家自然科学基金面上项目(81473667). （81473667）
