天津中医药2016，Vol.33Issue(5)：274-278,5.DOI:10.11656/j.issn.1672-1519.2016.05.05
血府逐瘀方治疗冠心病心绞痛随机对照试验的Meta分析
Xuefu Zhuyu prescription for the treatment of angina pectoris:a Meta-analysis of randomized controlled trials
摘要
Abstract
[Objective] To quantitative evaluate the clinical effects of coronary heart disease with angina pectoris by Xuefu Zhuyu prescription. [Methods] Retrieving total 8 databases, such as Cochrane Library, Pubmed, Web of Science, Elsevier, CNKI, Wanfang, CBM, and VIP, the literatures as of December 2015 were published in both English and Chinese, which were absorbed into angina pectoris clinical randomized controlled trials that the treatment of Xuefu Zhuyu prescription alone or merged with conventional Western medicine, and compared with the treatment of conventional Western medicine. All reports which were selected in accordance with strict inclusion criteria would be analyzed with Revman 5.3 software for statistical analysis, end effect index to relative risk (RR) and 95%confidence interval (CI). [Results] A total of 10 articles were 745 cases of patients with angina pectoris included in the standard. The result showed that the treatment group effect was better than the control group (P<0.00001;RR=1.27;95%CI=[1.19, 1.37]). No serious adverse reactions of Xuefu Zhuyu prescription had been reported. [Conclusion] Application in the treatment of angina pectoris, Xuefu Zhuyu prescription could improve the efficiency, and had the characteristics of less adverse reaction. However, due to effect of the low quality of the absorbed studies of samples, publication bias and other factors, there has to be more high-quality, multiple-center, large-sample randomized controlled trials to validate the curative effect of Xuefu Zhuyu prescription.关键词
血府逐瘀方/冠心病心绞痛/Meta分析/随机对照试验Key words
Xuefu Zhuyu prescription/coronary heart disease angina pectoris/Meta-analysis/randomized controlled trial分类
医药卫生引用本文复制引用
高树明,姚璐,李沛纯,杨帅,李琳,高杉,于春泉..血府逐瘀方治疗冠心病心绞痛随机对照试验的Meta分析[J].天津中医药,2016,33(5):274-278,5.基金项目
国家重点基础研究发展计划("973"计划)项目(2014CB542902) （"973"计划）
国家自然科学基金资助项目(81403198). （81403198）
