摘要
Abstract
[Objective] To evaluate on the therapeutic effect of Sini powder and Tongxieyao prescription and Western medicine on irritable bowel syndrome of randomized controlled trials. [Methods] By computer retrieval CNKI (2005-2015), VIP (2005-2015) and WF (2005-2015), supplemented by manual retrieval of Tianjin University of Chinese medicine library item database. Comprehensive collection of randomized controlled trials about Sini powder and Tongxieyao prescription, to extract information and according to the Cochrane Reviewer faced 5.0 quality assessment, statistical analysis by RevMan 5.2 software. [Results] 12 clinical randomized controlled trials were included, total 1778 patients. Meta analysis showed:the clinical total effective rate:combined effects of RR=1.30, 95%CI (1.14, 1.48), merge effect quantity inspection, Z=3.95, P<0.00001. [Conclusion] It has significant advantage of Sini powder and Tongxieyao prescription and Western medicine in the treatment of irritable bowel syndrome in clinical total effective rate. But, all of the above indexes, most directly using simple comparison of the total effective rate, and lack of symptoms integral evaluation, therefore, in improvement the symptoms of irritable bowel syndrome, such as abdominal pain, diarrhea, defecation urgency, body tired, anorexia, etc., it is not comprehensive, systematic, intuitive reflected of the advantage of comparison Sini powder and Tongxieyao prescription and Western medicine. Because the quality of included literature is not high, the above conclusion still needs more high-quality randomized, double-blind, placebo-controlled experiment to verify.关键词
四逆散合痛泻要方/随机对照试验/方法学/质量评价Key words
Sini powder and Tongxieyao prescription/randomized controlled trial/methodology/quality evaluation分类
医药卫生