天津中医药2016，Vol.33Issue(5)：316-320,5.DOI:10.11656/j.issn.1672-1519.2016.05.16
中药保护关节软骨的作用机制研究进展
The progress of traditional Chinese medicine protection mechanisms of articular cartilage
摘要
Abstract
Through literature review, based on morphology, cytokines, overview of chondrocyte apoptosis and other aspects, this article outlined the mechanism of traditional Chinese medicine for theprotecting articular cartilage. Traditional Chinese medicine in the treatment of arthritis, primarily through reducing damage, delay differentiation and degeneration and promote cartilage repair work, which included:1) inhibit cartilage cell expression of inflammatory cytokines and produce;2) inhibit MMPs expression of articular cartilage;3) promote growth factor expression; 4) promote collagen formation; 5) promote the articular cartilage cell proliferation; 6) inhibition of articular cartilage cell apoptosis, etc.关键词
中药/关节软骨/机制Key words
traditional Chinese medicine/articular cartilage/mechanism分类
医药卫生引用本文复制引用
张磊,王朝旭,吴沅皞,刘维..中药保护关节软骨的作用机制研究进展[J].天津中医药,2016,33(5):316-320,5.基金项目
国家自然科学基金项目(81473635),国家自然科学基金项目(81503506) （81473635）
天津市高等学校科技发展基金计划项目(20120220) （20120220）
天津市卫生和计划生育委员会中医中西医结合科研课题项目(2015091). （2015091）
